What is it?

Guggul lipid comes from the yellowish sap gathered from the bark of the small Commiphoral mukul tree, which is a relative of myrrh. Gugguls are currently being marketed as the next fat-loss miracle, and while we've kept a close eye on it to see if it does ever match up to the hype, there hasn't been much evidence so far... at least in the way of human research. Until there are good, quality human studies, we're leaving this one on the shelf. That doesn't mean it should be completely forgotten, however. If heart health concerns you, this one may be worth checking out, as it's been shown to reduce "bad" (LDL) cholesterols.

How it works

Research with laboratory animals suggests guggul may work by helping enhance thyroid functioning. This is significant because the thyroid gland produces hormones that are needed to regulate metabolism. Studies show guggul may change thyroid hormone metabolism, increasing levels of circulating T3, or triiodothyroxine, a thyroxine metabolite known to raise overall metabolism. Theoretically at least, this should help the body burn significantly more fat. If this benefit is shown in humans as well, guggul will likely gain popularity for helping fight the accumulation of fat. But for now, it's only been shown to be true in little furry creatures.

What does the science say?

While there is some evidence to suggest guggul may help lower bodyfat accumulation, unfortunately, the data simply just isn't all in. However, other studies have confirmed the benefits of guggul on the cardiovascular system. In one 16-week study, 40 patients with heart disease were given twice daily divided doses of 4.5 grams of guggul lipid. The results were a 21.75% decrease in blood fats, including LDL, VLDL, and triglycerides, and a 35% increase in HDL. In this study, guggul lipid also reduced platelet stickiness, a factor in blood clotting, poor circulation, and stroke risk.

How to take it

Doses vary depending on the desired benefit: for weight loss�0 to 60 mg three times per day with meals; to lower high cholesterol�5 mg three times daily of guggul lipid.

Important Tip: Look for products that have been standardized to 25 mg guggulsterones (also spelled gugulsterones and guggalsterones) per dose. Avoid the crude gum—it's not well tolerated by the human body and can cause gastrointestinal distress.